Ingestion may cause burning of the mouth, throat and stomach. Degenerative changes of the liver, heart, brain, and damage of the spleen, pancreas, central nervous system and kidneys. Death can occur in hours or days. Acute effects of methanol can cause blindness and central nervous system depravation. Acute effects due to inhalation and skin and eye contact range from irritation of eyes, skin, and mucous membranes to burning, difficulty breathing, respiratory tract injury, discoloration of skin, roughness and first degree burns. Aggravated sensitization response (extreme difficulty breathing, extreme rash and irritation
is also noted).

Repeated ingestion of small quantities may cause gastrointestinal irritation, visual impairment, blindness and other systemic effects.

Repeated exposure increases the cancer risk, and can also lead to conjunctivitis, dermatitis, metabolic acidosis, second degree burns, numbness, a persistent itching rash, headaches, stomach aches, serious respiratory impairment, kidney injury, and pulmonary sensitization. Neuropsychological effects may include sleep disorders, irritability, altered sense of balance, memory deficit, loss of concentration and mood alterations. Menstrual disorders and secondary sterility have occurred in women.